广西医学2018，Vol.40Issue(7)：733-735,3.DOI:10.11675/j.issn.0253-4304.2018.07.01
慢性乙型肝炎患者肾功能损害情况及其危险因素
Analysis of renal function damage and its risk factors in patients with chronic hepatitis type B
摘要
Abstract
Objective To investigate the renal damage and its risk factors in patients with chronic hepatitis type B(CHB). Methods A total of 410 patients with CHB without antiviral treatment were enrolled in this study.The estimated glomerular filtration rate (eGFR) calculated by Modification of Diet in Renal Disease(MDRD) was used to assess renal function damage.The related influencing factors of renal function damage were analyzed by multivariate logistic regression model.Results The incidence rate of renal function damage was 19.75%(81/410) in CHB patients. The results of multivariate analysis showed that male and age >50 years were the independent risk factors for renal function damage in CHB patients(all P<0.05).Conclusions Some CHB patients might suffer renal function damage before antiviral therapy.Male patients or patients older than 50 years have a higher risk for renal function damage.关键词
慢性乙型肝炎/肾功能损害/危险因素Key words
Chronic hepatitis type B/Renal function damage/Risk factor分类
医药卫生引用本文复制引用
王慧雯,李慧姣,杜漫,刘宇,郭莉,黄艳芬,陆惠洁,江建宁..慢性乙型肝炎患者肾功能损害情况及其危险因素[J].广西医学,2018,40(7):733-735,3.基金项目
广西自然科学基金(2014GXNSFDA118023) （2014GXNSFDA118023）
