化学工程2018，Vol.46Issue(4)：16-21,6.DOI:10.3969/j.issn.1005-9954.2018.04.004
反应精馏合成氯乙酸甲酯新工艺过程研究
New process of synthesis of methyl chloroacetate by reactive distillation
摘要
Abstract
A new technology for the synthesis of methyl chloroacetate by reactive distillation was presented.Firstly,the chemical software was used to simulate and optimize the reaction distillation process,the results are as follows:theoretical plates numbers of distillation section is 6,theoretical plates numbers of reaction section is 10,the reflux ratio is 0.6,the reflux ratio of water phase is 0.15,the mass fraction of chloroacetic acid is about 20 percent to 35 percent,and the mass fraction of methyl chloroacetate in the top of the column is 93.3 percent.And then the dehydrating tower is optimized,the purity of methyl chloroacetate after purification is 99.98 percent.On the basis of simulation,the reaction distillation experiment was carried out.And finally it is determined that the reflux ratio is 1,the reflux ratio of water phase is 0.2,the mass fraction of chloroacetic acid is about 28 percent to 40 percent,the mass fraction of methyl chloroacetate in the organic phase from the top of the column is 93.74 percent.After the crude ester is simply dehydrated,the mass fraction of methyl chloacetate is higher than 99.5 percent.The experimental results of the distillation column were compared with the simulation results,and the errors were less than 10％,which verified the reliability of the simulation.关键词
反应精馏/氯乙酸甲酯/模拟/小试实验Key words
reactive distillation/methyl chloroacetate/simulation/small experiment分类
化学化工引用本文复制引用
李柏春,杜慧丽,薛西西,邓会宁..反应精馏合成氯乙酸甲酯新工艺过程研究[J].化学工程,2018,46(4):16-21,6.
