解剖学杂志2018，Vol.41Issue(2)：129-134,6.DOI:10.3969/j.issn.1001-1633.2018.02.001
水通道蛋白在人喉组织的表达
Expression of aquaporins in human larynx
摘要
Abstract
Objective:To investigte the expression and localization of aquaporins in larynx Methods:RT-PCR,Western blotting and immunohistochemistry were employed to identify aquaporin activity in the larynx.Results:AQP1 was expressed on the cilia of the pseudostratified ciliated columnar epithelium,in vascular endothelial cells of the lamina propria mucosae and in glial cells.AQP3 was expressed on the membrane of squamous epithelial cells and lamina propria glandular cells of the laryngeal mucosa and on the basal lateral membrane of the pseudostratified ciliated columnar epithelium.Conclusion:To our knowledge,this is the first report of the expression of AQP1 on cilia.We further confirm that the expression of laryngeal AQPs is an important aspect of laryngeal histology and might be helpful for understanding the functions of AQPs in the larynx.关键词
喉/喉室/水通道蛋白1/水通道蛋白3/发声Key words
larynx/laryngeal ventricle/aquaporin 1/aquaporin 3/vocalization引用本文复制引用
吴庆田,石海红,张国福,张玉萍,侯霞..水通道蛋白在人喉组织的表达[J].解剖学杂志,2018,41(2):129-134,6.基金项目
National Natural Science Foundation of China(31400651),Heilongjian Provincial Natural Science Fund(LC201416),Foundation of Department of Public Health of Heilongjiang Province of China (2009-345),and Key Program of Jiamusi University of China (SZ2009005) （31400651）
