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基于突触离子通道动力学神经元网络的高效并行仿真算法

彭霞 王直杰 韩芳 顾晓春

计算机工程与科学2018,Vol.40Issue(4):609-615,7.
计算机工程与科学2018,Vol.40Issue(4):609-615,7.DOI:10.3969/j.issn.1007-130X.2018.04.006

基于突触离子通道动力学神经元网络的高效并行仿真算法

A high-efficient parallel neuronal network simulation algorithm based on synaptic ion channel kinetic

彭霞 1王直杰 1韩芳 1顾晓春1

作者信息

  • 1. 东华大学信息科学与技术学院,上海201620
  • 折叠

摘要

Abstract

In the field of computational neuroscience,the parallel simulation of large-scale neuronal networks plays a very important role in exploring and revealing the information processing mechanism of the brain.In order to accelerate the large-scale neuronal network simulation,an efficient parallel neuronal network algorithm based on synaptic neurotransmitter-receptor ion channel kinetic characteristics is proposed.By analyzing the information transmission mechanisms and the neurotransmitter-receptor ion channel kinetic characteristics of the chemical synapse,we propose an idea of the separation of presynaptic neurotransmitter computing from postsynaptic receptor computing.The new idea enhances the independence of the two concentration calculation:neurotransmitter emitted by presynaptic neurons,and the bound postsynaptic receptors.During each synaptic current computing,the new idea reduces the coupling degree of the presynaptic neuron and the postsynaptic neuron.Based on the new idea,we design a parallel algorithm for parallel neuronal network simulation based on synaptic ion channel kinetic.Simulation results show that the algorithm is efficient.

关键词

神经元网络/递质-受体/离子通道/突触电流/耦合度

Key words

neuronal network/neurotransmitter-receptor/ion channel/synaptic current/coupling degree

分类

信息技术与安全科学

引用本文复制引用

彭霞,王直杰,韩芳,顾晓春..基于突触离子通道动力学神经元网络的高效并行仿真算法[J].计算机工程与科学,2018,40(4):609-615,7.

基金项目

国家自然科学基金(11572084,11472061) (11572084,11472061)

计算机工程与科学

OA北大核心CSCDCSTPCD

1007-130X

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