实用临床医药杂志2018，Vol.22Issue(9)：16-19,4.DOI:10.7619/jcmp.201809004
食道癌伴抑郁患者脑电频率变化与额叶认知功能损害关联研究
Study on the relationship between change of brain electrical frequency and cognitive functional impairment in patients with esophageal cancer and depression
曹音 1邹凌 2谢惠 3胡莉钧4
作者信息
- 1. 江苏省常州市第二人民医院神经内科,江苏常州,213003
- 2. 常州大学信息科学与工程学院、数理学院,江苏常州,213164
- 3. 江苏省常州市第二人民医院脑电图室,江苏常州,213003
- 4. 江苏省常州市第二人民医院放疗科,江苏常州,213003
- 折叠
摘要
Abstract
Objective To investigate the relationship between changes of electroencephalogram frequency and cognitive dysfunction in patients with esophageal cancer and depression.Methods A total of 60 patients with esophageal cancer complicated with depression were recruited in the study group and 60 normal controls were assessed for cognitive function of the frontal lobe and electroencephalogram (ECG).The study group was subdivided into with and without psychotic symptoms (PD and NPD groups).Beck's Depressive Self-Rating Scale (Beck Depression Scale) and Concise Psychiatric Inventory (BPRS) were used to assess the patient's clinical symptoms.Results Compared with the control group,the Stroop test and the number of color connection scores in the study group and the PD group were significantly prolonged,and the verbal fluency scores were significantly reduced.Compared with the control group,the Stroop test and digital color connection scores were prolonged in the NPD group.Compared with NPD group,the above indicators in PD group were significantly prolonged.The power of the forehead brainwaves α1,δ and θ in the study group was significantly higher than that in the control group.The multivariate analysis revealed that the power of α1 showed a significant difference in left and right forehead brainwave powers between the study group and the control group.After controlling the Beck depression score,the left frontal α1 wave and θ wave power of the study group were negatively correlated with the verbal fluency score,and positively correlated with the digital color connection and the Stroop test.Conclusion The change of prefrontal brain electrical power is related to cognitive impairment in patients with esophageal cancer and depression.关键词
食道癌/抑郁/脑电频率/额叶/认知功能/相关性Key words
esophageal cancer/depression/EEG frequency/frontal lobe/cognitive function/correlation分类
医药卫生引用本文复制引用
曹音,邹凌,谢惠,胡莉钧..食道癌伴抑郁患者脑电频率变化与额叶认知功能损害关联研究[J].实用临床医药杂志,2018,22(9):16-19,4.
