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细胞活性氧荧光探针研究现状

周全 黄国阳 徐伟刚

军事医学2018,Vol.42Issue(1):72-76,5.
军事医学2018,Vol.42Issue(1):72-76,5.DOI:10.7644/j.issn.1674-9960.2018.01.018

细胞活性氧荧光探针研究现状

Current development of fluorescent probes for cellular reactive oxygen species

周全 1黄国阳 1徐伟刚1

作者信息

  • 1. 海军军医大学海军医学系潜水医学教研室,上海200433
  • 折叠

摘要

Abstract

Reactive oxygen species(ROS)plays an important role in physiological and pathological processes in cells. Different effects can be produced depending on the type and subcellular localization of ROS.Therefore,various fluorescent probes have been developed to quantify and localize ROS specifically.However,due to technical limitations,these probes have defects in specificity and stability.In this paper, we review existing cellular and mitochondrial ROS probes, and summarize their characteristics.

关键词

荧光探针/活性氧/线粒体

Key words

fluorescent probes/reactive oxygen species/mitochondria

分类

生物科学

引用本文复制引用

周全,黄国阳,徐伟刚..细胞活性氧荧光探针研究现状[J].军事医学,2018,42(1):72-76,5.

基金项目

国家自然科学基金资助项目(81772014) (81772014)

军事医学

OA北大核心CSTPCD

1674-9960

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