摘要
Abstract
Objective To study on the efficiency of radiotherapy and interventional therapy in the treatment process of pancreatic cancer and the effect on plasma β-endorphin(β-EP),prostaglandin E2(PGE2),calcitonin gene-related peptide(CGRP)and long-term survival rate.Methods A total of 100 patients with pancreatic cancer were considered as study objects and the clinical data were analyzed retrospectively.They were divided into observation group(n=52)and control group(n=48).The patients in the observation group were treated with radiotherapy and interventional therapy,while the patients in the control group were treated with inter-ventional therapy.The treatment effects were observed and compared.Results The total effective rate in the observation group was significant higher than that in the control group(χ2=5.565,P=0.018).The incidence rates of several adverse reactions in the observation group were significant lower than those in the control group(P<0.05).Before treatment,there were no significant different between the two groups about β-EP, PGE2,CGRP,and pain score(P> 0.05).But after treatment,the indexes including PGE2,CGRP and pain score in the observation group were lower than those of the control group(P<0.05),the β-EP and neoplasm necrosis volume in the observation group were higher than those of the control group(P<0.05).The 3 years survival rate in the observation group was significant higher than that in the control group(P< 0.05). Conclusion Combined using radiotherapy and interventional therapy could reduce the levels of plasma β-EP, PGE2,CGRP in patients with pancreatic cancer,and relieve the pain of patients,improve the quality of life of patients with better safety,and this method is value to recommend in clinic.关键词
放疗/介入治疗/胰腺癌/治疗效果Key words
radiotherapy/interventional therapy/pancreatic cancer/treatment effect分类
医药卫生
