临床口腔医学杂志2018,Vol.34Issue(5):274-277,4.DOI:10.3969/j.issn.1003-1634.2018.05.006
ZnO-AlBw复合材料对变形链球菌致病基因的影响研究
Study on the function of the ZnO-AlBw on virulence genes of Streptococcus mutans
武钺 1金建烽2
作者信息
- 1. 昆明市口腔医院口腔内科 云南 昆明 650110
- 2. 昆明市口腔医院口腔综合科 云南 昆明 650110
- 折叠
摘要
Abstract
Objective:To explore the function of the ZnO-AlBw on virulence genes of Streptococcus mutans.Meth-ods:The relative expression of gtfB、gtfC and gtfD of Streptococcus mutans were affected by ZnO-AlBw which was fabricated via sol-gel method. The results were analyzed by SEM,XRD,LSCM and RT-PCR. Results:The structure of AlBw was changed by ZnO nanoparticles.The Streptococcus mutans cell membrane were destroyed by ZnO-AlBw.The gtfBC genes were down-regulated,and gtfD gene was up-regulated.Conclusion:ZnO-AlBw composites had antibacterial properties.The rela-tive expression of gtfBCD of Streptococcus mutans were influenced by ZnO-AlBw.关键词
氧化锌-硼酸铝晶须/变形链球菌/荧光值/胞膜/致病基因Key words
ZnO-AlBw/Streptococcus mutans/Fluorescence value/Cell membrane/Virulence gene分类
生物科学引用本文复制引用
武钺,金建烽..ZnO-AlBw复合材料对变形链球菌致病基因的影响研究[J].临床口腔医学杂志,2018,34(5):274-277,4.