南京农业大学学报2018，Vol.41Issue(3)：534-541,8.DOI:10.7685/jnau.201705024
脱氧雪腐镰刀菌烯醇对蛋鸡生产性能、血液指标和抗氧化能力的影响
Effects of deoxynivalenol on performance,blood indices and antioxidant capacity in laying hens
摘要
Abstract
[Objectives]This study was conducted to investigate the effects of deoxynivalenol(DON)on performance,egg quality, blood routine,serum biochemical parameter and liver oxidation indices in laying hens. [Methods]One hundred twenty 26-week-old Hy-Line laying hens with weight(1.90±0.2)kg and similar egg production rate were randomly allotted to 6 groups with 4 replicates per group and 5 laying hens per replicate,the laying hens in the test groups were fed one of the 5 kinds of diets[1,5,10,20 and 50 mg·kg-1DON exposed daily via intragastric administration]for 6 weeks,and laying hens in the control group were fed the same equivalent normal saline as test groups in the same protocol. [Results]Compared with control,albumen height and Haugh unit value in different DON groups significantly increased,but the count of WBC and PLT remarkably decreased(P<0.05 or P<0.01). In 10 mg·kg-1DON group,egg production rate decreased(P<0.01),and RBC,HGB and HCT in blood significantly increased compared with control group(P<0.01). Besides,when doses of DON was added more than 10 mg·kg-1,the HGB,RBC and HCT in blood,the concentration of UREA and levels of AST,ALT and ALP in serum and the concentration of NO and MDA in liver were significantly elevated(P<0.05 or P<0.01),but eggshell color and the activity of T-AOC,GSH-Px and SOD in liver significantly reduced(P<0.05 or P<0.01). However,levels of T-AOC and SOD in 5 mg·kg-1DON group dramatically increased(P<0.05). [Conclusions]It is concluded that the supplementation of DON could significantly affect the blood coagulation function of laying hens,and addition of 10 mg·kg-1DON could cause the decrease of egg production rate and egg quality,the organ damage of liver and kidney and the reduction of antioxidant ability in liver of laying hens.关键词
脱氧雪腐镰刀菌烯醇(DON)/蛋鸡/生产性能/血液指标/抗氧化Key words
deoxynivalenol/laying hen/performance/blood indices/antioxidant capacity分类
农业科技引用本文复制引用
郭晋丽,赵志辉,郭文博,孙真真,杨俊花,张德福..脱氧雪腐镰刀菌烯醇对蛋鸡生产性能、血液指标和抗氧化能力的影响[J].南京农业大学学报,2018,41(3):534-541,8.基金项目
上海市农委科技兴农重点攻关项目[沪农科攻字(2013)第3-8] （2013）
上海市自然科学基金项目(17ZR1418800) （17ZR1418800）
