同济大学学报(医学版)2018,Vol.39Issue(2):22-25,4.DOI:10.16118/j.1008-0392.2018.02.005
银屑病靶向外用药物的研究进展
Research advances of topical treatment of psoriasis
摘要
Abstract
In recent years, the research progresses in immunological mechanisms of psoriasis and genetic engineering have brought the prospect in treatment of psoriasis. Several new agents selectively targeting the small molecules of cytokines and signaling pathways are available. The phase I and II clinical trials on inhibitors of JAK/STAT, PED4, IRS-1,VEGF receptors and TrkA are underway, which would provide more choices for topical treatment of psoriasis in the future.关键词
银屑病/外用药/信号通路/小分子抑制剂Key words
psoriasis/topical treatment/signaling pathways/small molecules inhibitor分类
医药卫生引用本文复制引用
黄韬..银屑病靶向外用药物的研究进展[J].同济大学学报(医学版),2018,39(2):22-25,4.基金项目
国家自然科学基金(81673050,81301356) (81673050,81301356)
上海市自然科学基金(16ZR1426800) (16ZR1426800)