世界中医药2018，Vol.13Issue(4)：826-829,4.DOI:10.3969/j.issn.1673-7202.2018.04.010
滋肾育胎丸联合黄体酮注射液治疗先兆流产患者的临床效果
Clinical Observation on 60 Cases of Threatened Abortion Treated by Zishen Yutai Pill Combined with Progesterone Injection
摘要
Abstract
Objective:To observe the clinical effects of Zishen Yutai Pill combined with progesterone injection in the treatment of threatened abortion.Methods:A total of 60 cases of 4 to 9 gestational weeks of threatened abortion patients in our hospital were randomly divided into treatment group and control group,with 30 cases in each.The control group was given daily intramuscular in-jection of progesterone injection 40 mg.The treatment group was given the Chinese herbal medicine Zishen Yutai pill on the basis of the control group.Two groups were 7 days for a course of treatment,with a total of 3 courses.The levels of serum chorionic gonado-tropin(β-HCG),progesterone(P)and estradiol(E2)were measured before and after treatment for 1,2 and 3 weeks.TCM syn-dromes before and after treatment were compared.The clinical efficacy of different age,gestational age and spontaneous abortion in the treatment group was compared with that in the treatment group.Results:The comprehensive effect of the treatment group and the control group was 90% and 77% respectively.The therapeutic effect of the treatment group was significantly higher than that of the control group(P<0.05).The levels of β-HCG,P and E2in the serum of the two groups were significantly higher than those before treatment(P<0.01).The subjects in the two groups were significantly higher than those in the control group(P<0.01). The levels of serum β-HCG and E2were not significantly different between the two groups(P>0.05).After 1,2 and 3 weeks of treatment,the levels of progesterone(P)increased significantly(P<0.01).There was no significant difference in the total effec-tive rate of the subjects with different age groups,gestational age and spontaneous abortion in the treatment group(P>0.05). Conclusion:The clinical curative effect of Zishen Yutai Pill combined with progesterone injection on the treatment of threatened a -bortion is not significantly correlated with the age,gestational age and spontaneous abortion of pregnant women.The improvement of TCM symptoms is very significant,and the levels of P were significantly increased.关键词
先兆流产/滋肾育胎丸/绒毛膜促性腺激素/孕酮/雌二醇Key words
Threatened abortion/Zishen Yutai pill/Chorionic gonadotropin/Progesterone/Estradiol分类
医药卫生引用本文复制引用
韩凤娟,李佳,田苗,张茗..滋肾育胎丸联合黄体酮注射液治疗先兆流产患者的临床效果[J].世界中医药,2018,13(4):826-829,4.基金项目
罗元恺滋肾育胎丸中青年科研基金(140209) （140209）
国家中医药管理局国家中医临床研究基地业务建设科研专项(JDZX2012038) （JDZX2012038）
