世界中医药2018，Vol.13Issue(4)：830-833,4.DOI:10.3969/j.issn.1673-7202.2018.04.011
左金丸治疗对肝火犯胃证反流性食管炎患者胃肠道自主神经功能的影响
Zuojin Pill in Treating Gastrointestinal Autonomic Nerve Function of Reflux Esophagitis with Liver Fire Invading Stomach Syndrome
摘要
Abstract
Objective:To observe and analyze the effects of Zuojin Pill on gastrointestinal autonomic nerve function in treating re -flux esophagitis with liver fire invading stomach syndrome.Methods:A total of 78 cases of reflux esophagitis patients with liver fire invading stomach syndrome who were admitted in our hospital from January 2016 to January 2017 were randomly divided into obser-vation group and control group,with 39 cases in each group.The control group was given western medicine Omeprazole Enteric-coa-ted Capsules with Mosapride Citrate Tablets for oral treatment,and observation group was given oral administration of Zuojin Pill. The clinical symptoms,endoscopic grading,autonomic detection value,and the clinical curative effect evaluation before and after treatment were recorded respectively.Results:After 1 month of treatment,1)the total effective rate of treatment group was 84.61%,and the total effective rate of observation group was 94.44%,which was better than 84.61% in the treatment group(P<0.05);2)under endoscopy,the degree of improvement in the observation group was significantly better than the control group(P<0.05);3)the clinical symptoms scores and RDQ of two groups were lower than those before treatment(P<0.05),and the ob-servation group was better than the control group(P<0.05);4)after treatment,LF of both groups were increased,and HF de-creased(P<0.05).The observation group was better than the control group(P<0.05).Conclusion:Zuojin Pill in treating reflux esophagitis with liver fire invading stomach syndrome can more effectively regulate the patient's gastrointestinal autonomic nerve function,relieve the clinical symptoms of acid reflux,pain behind the sternum,and improve clinical curative effect,which is worthy of promotion and application.关键词
左金丸/反流性食管炎/肝火犯胃/反流病诊断问卷评分/内镜分级/自主神经功能/临床疗效/机制Key words
Zuojin Pill/Reflux esophagitis/liver fire invading stomach/RDQ/Endoscopic grading/Autonomic nervous func-tion/Clinical curative effect/Mechanism分类
医药卫生引用本文复制引用
张博,李乔,谢冰昕..左金丸治疗对肝火犯胃证反流性食管炎患者胃肠道自主神经功能的影响[J].世界中医药,2018,13(4):830-833,4.基金项目
北京中医药科技发展资金青年研究项目(QN2014-013) （QN2014-013）
