世界中医药2018，Vol.13Issue(4)：834-837,4.DOI:10.3969/j.issn.1673-7202.2018.04.012
黄葵胶囊联合还原型谷胱甘肽在糖尿病肾病中的应用
Study on Application of Huangkui Capsule and GSH in Treating Diabetic Nephropathy
摘要
Abstract
Objective:To study the effectiveness of Huangkui capsule and GSH in treating diabetic nephropathy.Methods:A total of 128 patients with diabetic nephropathy who were admitted and treated in our hospital from February 2016 to January 2017 were randomly divided into control group of 64 cases and observation group of 64 cases.Patients in the control group were treated with GSH,while patients in the observation group were given Huangkui capsule and GSH.The effectiveness was determined by observ-ing the changes of blood sugar,blood fat and kidney function, and monitoring the changes of GGT, AOPP and IL-1βlevel.Re-sults:The clinical efficiency for patients in the observation group was 90.6%,which was higher than 76.6% in the control group (P<0.05);The indexes of blood sugar,blood fat and kidney function for patients in the observation group were lower than that of the control group(P<0.05);The levels of GGT,AOPP and IL-1βfor patients in the observation group were lower than that of the control group after treatment(P<0.05).Conclusion:Huangkui capsule and GSH are good in controlling blood glucose,lipid metabolic disorder and improving renal function,with satisfactory clinical effects.The mechanism may be associated with regulating the levels of GGT,AOPP and IL-1βto reduce the body state of oxidative stress damage, micro inflammation reaction, which is worthy of clinical promotion.关键词
糖尿病肾病/黄葵胶囊/还原型谷胱甘肽/糖脂代谢/肾功能Key words
Diabetic nephropathy/Huangkui capsule/GSH/Glucose lipid metabolism/Renal function/GGT/AOPP/IL-1β分类
医药卫生引用本文复制引用
孙道崎,黄德芳,薛俊,张安星,俞丹..黄葵胶囊联合还原型谷胱甘肽在糖尿病肾病中的应用[J].世界中医药,2018,13(4):834-837,4.基金项目
2014年新疆克孜勒苏柯尔克孜自治州科研项目(35) （35）
