实用妇产科杂志2018，Vol.34Issue(4)：286-290,5.
不同高雄激素血症表型多囊卵巢综合征患者临床特征分析
Analysis of Clinical Features of PCOS Patients with Different Hyperandrogen Phenotypes
摘要
Abstract
Objective:To investigate the clinical and metabolic characteristics of PCOS patients with different phenotypes of hyperandrogenism.Methods:A retrospective analysis from April 2013 to July 2017 of 683 PCOS patients treated in our hospital,according to the serum AND and T levels were divided into 4 subgroups:high AND with high T group(group A);only high AND group (group B);only high T group (group C);non-hyperandrogenism group(group D).Fifty healthy women were selected as control group (group NC).The clinical and biochemical indexes of the five groups were analyzed.Results:Acanthosis,acne and incidence of seborrheic hirsutism score,LH、LH/FSH in the PCOS patients were significantly higher than the control group(P ＜ 0.05),patients with high AND(A,B group) showed higher levels of FAI,FINS,HOMA-IR,LDL,TC than the control group (P ＜0.05),and the level of LH 、LH/FSH、SHBG 、DHEAS、FAI in the PCOS patients with high AND(A,B group) were significantly different with the non-hyperandrogenism PCOS group (D group) (P ＜ 0.05).Conclusions:PCOS patients with hyperandrogenism are more likely to have reproductive hormone abnormalities,HI,IR and lipid metabolism.The hormone levels and abnormal metabolic disorder in patients with high AND is more serious.We should pay more attention to the detection of serum AND.关键词
多囊卵巢综合征/高雄激素血症/雄烯二酮/睾酮Key words
Polycystic ovary syndrome/Hyperandrogenism/Androstenedione/Testosterone分类
医药卫生引用本文复制引用
牛静云,侯丽辉,寇丽辉,孟小钰,王颖,曲玉芳..不同高雄激素血症表型多囊卵巢综合征患者临床特征分析[J].实用妇产科杂志,2018,34(4):286-290,5.基金项目
国家中医药管理局国家中医临床研究基地业务建设科研专项课题(编号:JDZX2012039) （编号:JDZX2012039）
