实用医学杂志2018，Vol.34Issue(8)：1339-1342,4.DOI:10.3969/j.issn.1006-5725.2018.08.029
不同麻醉深度对老年患者围术期脑氧代谢及术后认知功能的影响
Effects of different anesthesia levels on perioperative cerebral oxygen metabolism and postoperative cogni-tive function in elderly patients
摘要
Abstract
Objective To investigate the effects of different levels of anesthesia on perioperative cerebral oxygen metabolism and postoperative cognitive function in the elderly patients. Methods One hundred elderly pa-tients receiving gastric cancer surgery were divided into two groups:group D(BIS value 30-39) and group L(BIS value 50-59). Blood samples were collected at T0,T1,T2,T3 and T4. Da-jvO2 and CERO2 were calculated at the same time.MMSE score was recorded at the time point of 1,3 and 7 d after operation.Results Compared with the T0,Da-jvO2 and CERO2 were both decreased in the two groups at T2-T4(P<0.05).Compared with the group L, the group D were decreased more obviously(P < 0.05). Compared with preoperative score,MMSE score was de-creased at the time point of 1,3d in the group L as well as 1d in the group D(P<0.05).Compared with the group L,group D was significantly increased at the time point of 1 and 3 d(P < 0.05). Conclusion BIS value was maintained at 30-39 can decrease perioperative cerebral oxygen metabolism and improve postoperative cognitive function in the elderly patients.关键词
胃癌/麻醉深度/老年患者/脑氧代谢/术后认知功能障碍Key words
gastric cancer/depth of anesthesia/elderly patients/cerebral oxygen metabolism/postoperative cognitive dysfunction引用本文复制引用
孔岚,章云飞..不同麻醉深度对老年患者围术期脑氧代谢及术后认知功能的影响[J].实用医学杂志,2018,34(8):1339-1342,4.基金项目
河南省科技攻关计划项目(编号:162102310335) （编号:162102310335）
