生殖医学杂志2018，Vol.27Issue(5)：489-493,5.DOI:10.3969/j.issn.1004-3845.2018.05.019
嵌合体胚胎:移植还是丢弃
Mosaic embryo:transplant or discard
摘要
Abstract
A large proportion of preimplantation embryos were produced during IVF,which contain two or even more cytogenetically different cell lines,and called mosaicism.Although the mosaicism of cleavage and blastocyst have been discovered for more than two decades,the exact incidence of mosaicism and its effect on embryonic development outcome remain unclear.With the advancing of cytogenetic technology,for example high-resolution next-generation sequencing(NGS),detection of mosaicism becomes more sensitive.Recent research found that mosaic embryos had lower implantation rate than embryos with normal chromosomes.However,some mosaic embryos can lead to live birth.How to deal with mosaic embryos and follow-up after mosaic embryo transfer is critical.关键词
嵌合体/有丝分裂/胚胎活检/胚胎移植Key words
Mosaicism/Mitosis/Embryo biopsy/Embryo transfer引用本文复制引用
刘茜桐,田莉,解晋琳,师娟子..嵌合体胚胎:移植还是丢弃[J].生殖医学杂志,2018,27(5):489-493,5.
