天津中医药2018，Vol.35Issue(5)：336-339,4.DOI:10.11656/j.issn.1672-1519.2018.05.05
清肺益肾方治疗痰热壅肺型老年肺炎临床疗效及对血清CD4+、CD8+水平的影响
Clinical effect of Qingfei Yishen decoction on senile pneumonia and its effect on serum CD4+and CD8+levels
摘要
Abstract
[Objective]To explore the curative effect of Qingfei Yishen decoction on the senile pneumonia (heat obstruct pulmonary syndrome)and the impact on serum CD4+and CD8+levels. [Methods]Senile pneumonia patients were randomly divided into control group and treatment group,control group given anti-inflammatory,eliminating phlegm treatment to smooth wheezing,antifebrile;on the basis of the control treatment,the treatment group was given Qingfei Yishen decoction.Clinical curative effect was compared between the two groups before and after treatment,and follow-up 1 month,like routine blood,c-reactive protein,symptom scores,imaging,the change of serum level of CD4+,CD8+.[Results]The total effective rate was 80.00% in the control group,and the treatment group was significantly higher than the control group (96.67%,P<0.05).The scores of cough,yellow phlegm and thirst symptoms in the treatment group were significantly lower than those in the control group (P<0.05).After treatment,the leukocyte count,neutrophil ratio,c-reactive protein,and chest CT scores were significantly lower than those in the control group (P<0.05). CD4+in the treatment group was increased in the treatment group (P<0.05,P<0.01),CD8+in the treatment group showed a significant decrease than those in the control group (P<0.05). [Conclusion]The curative effect of Qingfei Yishen decoction of senile pneumonia(heat obstruct pulmonary syndrome)is significant,and its mechanism may be related to reducing inflammatory response and regulating immunity.关键词
清肺益肾/炎症反应/免疫Key words
Qingfei Yishen decoction/senile pneumonia/immunization分类
医药卫生引用本文复制引用
孟泳,芦晓帆,王艳梅,李彬,甘德堃..清肺益肾方治疗痰热壅肺型老年肺炎临床疗效及对血清CD4+、CD8+水平的影响[J].天津中医药,2018,35(5):336-339,4.基金项目
河南省科技厅科技攻关计划项目(15212310107). （15212310107）
