同位素2018，Vol.31Issue(2)：123-128,6.
同位素稀释质谱法在临床参考系统中的应用
Applications of Isotope Dilution Mass Spectrometry in Clinical Reference Measurement System
摘要
Abstract
Traceability is essential for standardization and harmonization of clinical analytical results.The measurement result can be comparable to a reference through a documented unbroken chain of calibrations each contribution to the measurement uncertainty.Reference measurement procedure defined as providing measurement results fit for intended use in assessing measurement trueness of measured quantity values obtained from other measurement procedures for quantities of the same kind.Isotope Dilution Mass Spectrometry is a primary standard acknowledged as having the highest metrological qualities and whose value is accepted without reference to other standards.The review focused on the applications of IDMS in clinical reference measurement system including its principle,quantitative approaches and its related uncertainty.The updated status of JCTLM database was also commented in this review,which is helpful for those related researchers in clinical measurement,isotope application as well as metrological fields.关键词
溯源性/临床/同位素稀释质谱法/参考系统Key words
traceability/clinical/isotope dilution mass spectrometry/clinical reference measurement system分类
化学化工引用本文复制引用
全灿,李红梅..同位素稀释质谱法在临床参考系统中的应用[J].同位素,2018,31(2):123-128,6.基金项目
中国计量科学研究院基本科研业务费(21-AKY1615) （21-AKY1615）
国家重点研发计划“国家质量基础的共性技术研究与应用”重点专项课题(2017YFF0205803) （2017YFF0205803）
