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近视动物模型及发病机制的研究进展

郭芳 魏瑞华 吴绵绵 孙笑笑 张琰

眼科新进展2018,Vol.38Issue(5):490-496,7.
眼科新进展2018,Vol.38Issue(5):490-496,7.DOI:10.13389/j.cnki.rao.2018.0115

近视动物模型及发病机制的研究进展

Research advances in the animal models and pathogenic mechanisms of myopia

郭芳 1魏瑞华 1吴绵绵 1孙笑笑 1张琰1

作者信息

  • 1. 300384 天津市,天津医科大学眼科医院,天津医科大学眼科研究所,天津医科大学眼视光学院
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摘要

Abstract

Myopia has become a common disease all over the world,affecting the public quality of life and endangering public health.Exploring the pathogenesis is helpful for the prevention and treatment for myopia.However,the pathogenesis of myopia is still not clear,which makes it a hotspot and nodus.From the 1970s,the research on myopic animal models has made great breakthrough.It has provided valuable evidences and hint for mechanism research from the perspective of molecular mechanism,signal pathway,drug intervention,etc.In this paper,the research progess on common myopic animal models and pathogenesis will be reviewed.

关键词

近视/动物模型/发病机制/形觉剥夺性近视/光学离焦性近视

Key words

myopia/animal models/pathogenesis/form-deprivated myopia/lens-induced myopia

分类

医药卫生

引用本文复制引用

郭芳,魏瑞华,吴绵绵,孙笑笑,张琰..近视动物模型及发病机制的研究进展[J].眼科新进展,2018,38(5):490-496,7.

基金项目

国家级和市级大学生创新创业训练计划项目(编号:201710062036)National and Municipal College Students' Innovation and Entrepreneurship Training Program (No:201710062036) (编号:201710062036)

眼科新进展

OA北大核心CSTPCD

1003-5141

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