云南化工2018，Vol.45Issue(4)：80-82,3.DOI:10.3969/j.issn.1004-275X.2018.04.065
Box-Behnken响应面法优化藤梨根总黄酮超声提取工艺
Optimization of Extraction Technology of Total Flavones from Actinidia arguta Radix with Box-Behnken Design-response Surface Methology
王岩 1吴秋焱 1马翰林 1柳晓宇 1魏全浩 1郑浩 1朱立俏1
作者信息
- 1. 山东中医药大学 药学院,山东 济南 250355
- 折叠
摘要
Abstract
Objective:To optimize ultrasonic extraction technology of total flavones from Actinidia arguta Radix. Methods:The total flavones extraction rate as response value,the liquid material ratio、the ethanol volμme fraction and extraction time as three factors,derive the medicinal herbs with ultrasonic method,determine the content of total flavones with the use of spectrophotometer method at the wavelength of 510 nm,establish the box-behnken response surface of total flavones extraction with Design-expert 8.0.6 trial software and multivariate two regression analysis. Results:The optimμm extraction conditions were liquid material ratio 12.45,ethanol volμme fraction 78.09%,extraction time 39.66 min,total flavones extraction rate was 7.49%,predicted value was 7.58%,and deviation was 1.19%. Conclusion:The process is stable and feasible,and can be used in the industrialized production of total flavones from Actinidia arguta Radix.关键词
藤梨根/总黄酮/Box-Behnken响应面法/超声提取工艺Key words
Actinidia arguta Radix/total flavones/box-behnken response surface Methology/ultrasonic Extraction Technology分类
化学化工引用本文复制引用
王岩,吴秋焱,马翰林,柳晓宇,魏全浩,郑浩,朱立俏..Box-Behnken响应面法优化藤梨根总黄酮超声提取工艺[J].云南化工,2018,45(4):80-82,3.
