中国临床药理学杂志2018，Vol.34Issue(6)：640-642,3.DOI:10.13699/j.cnki.1001-6821.2018.06.009
维生素D2对高龄女性血清25-羟基维生素D的影响
Influence of intramuscular injection of vitamin D2 on serum 25-hydroxyvitamin D in aged women
摘要
Abstract
Objective To evaluate the influence of intramuscular injection of vitamin D2 on serum 25-hydroxyvitamin D in aged women.Methods A total of 40 aged women were randomly divided into treatment group and control group,each group 20 patients.Patients in treatment group were given vitamin D2 injection 6.0 × 105 U every month,intramuscular injection,for 3 months.Control group was given sunshine treatment The levels of serum 25-hydroxyvitamin D and calcium were evaluated and compared before treatment and after 8 months treatment.Results After 3 months treatment,serum 25-hydroxyvitamin D in treatment group and control group were (19.76 ± 3.28),(16.37 ± 3.01)ng · mL-1,with significant difference (P ＜ 0.01),and the levels of serum 25-hydroxyvitamin D in other times had no significant difference (all P ＞ 0.05).There was no significant difference in serum calcium between treatment and control group during 9 months (all P ＞ 0.05).Conclusion Vitamin D2 injection could be used to increase serum 25-hydroxyvitamin D level,and it had no effect on serum calcium.关键词
维生素D/血钙/老年女性Key words
vitamin D/calcium/aged women分类
医药卫生引用本文复制引用
杨其刚,钱素凤,边平达,寿张轩,陈锦平..维生素D2对高龄女性血清25-羟基维生素D的影响[J].中国临床药理学杂志,2018,34(6):640-642,3.基金项目
浙江省医药卫生科技计划基金资助项目(2016ZDA002,2018KY222) （2016ZDA002,2018KY222）
