中国医学装备2018，Vol.15Issue(5)：52-55,4.DOI:10.3969/J.ISSN.1672-8270.2018.05.015
磁共振弥散加权成像和动态增强成像对肝转移瘤的疗效评价及HIF-1α和VEGF表达
Evaluations of gene expression and curative effect of liver metastases by using the MR diffusion weighted imaging and dynamic contrast-enhanced imaging
摘要
Abstract
Objective: To explore the evaluations of the expressions of HIF-1α and VEGF and the curative effect of liver metastases by using MR diffusion weighted imaging and dynamic contrast-enhanced imaging. Methods: 60 patients with hepatoma were divided into observation group (n=30 cases) and control group (n=30 cases), and patients of observation group received the examination of MR diffusion weighted imaging and dynamic contrast-enhanced imaging and patients of control group received the routine examination. The clinically curative effects and the expression of HIF-1α and VEGF between the two groups were compared and analyzed. Results: The levels of HIF-1α and VEGF between the two groups before treatment were not significant. After they received treatment, the levels of HIF-1α and VEGF of observation group were significantly lower than that of the control group(t=15.061, t=12.346, P<0.05), respectively. Conclusion: Used MR diffusion weighted imaging and dynamic contrast-enhanced imaging to evaluate the curative effect of liver metastases and gene expression can effectively enhance the accuracy of diagnosis. Therefore, it should be widely popularized.关键词
磁共振弥散加权成像/动态增强成像/肝转移瘤/HIF-1α表达Key words
MR diffusion weighted imaging/Dynamic contrast-enhanced imaging/Liver metastases/HIF-1α expression分类
医药卫生引用本文复制引用
张旭,冯莉莉,张骞,麻增林..磁共振弥散加权成像和动态增强成像对肝转移瘤的疗效评价及HIF-1α和VEGF表达[J].中国医学装备,2018,15(5):52-55,4.基金项目
北京中医药大学2016年度基本科研业务费项目(中青年教师类)(2016-JYB-JSMS-072)"磁共振弥散成像对肝转移瘤中药结合放化疗疗效的早期定量评估" （中青年教师类）
