浙江医学2018，Vol.40Issue(5)：468-470,3.DOI:10.12056/j.issn.1006-2785.2018.40.5.2017-2642
改良型格拉斯哥预后评分对肝门部胆管癌患者手术治疗预后评估的价值研究
Modified Glasgow prognostic score in predicting postoperative survival of patients with cholangiocarcinoma
李金海 1朱明辉 1蔡宇 1张海峰 1薛迪新 1蒲青凡1
作者信息
- 1. 325200 温州医科大学附属第三医院肝胆外科
- 折叠
摘要
Abstract
Objective To assess the application of modified Glasgow prognostic score(mGPS) in predicting postoperative survival of patients with cholangiocarcinoma.Methods Clinical data of 64 patients with hilar cholangiacarcinoma undergoing radical resection were retrospectively analyzed.Patients were evaluated with mGPS based on the elevated values of preoperative C-reactive protein(CRP＞10mg/L) and albumin(Alb＜35g/L).There were 33 cases with mGPS 0,21 cases with mGPS 2 and 10 cases with mGPS 2.The clinical features,laboratory tests and postoperative survival were compared among three groups.Results There were no statistically significant differences in sex,age,tumor types,preoperative TBil,AFP,CA19-9,TNM stages and tumor differentiation among 3 groups (P ＞0.05);while there was significant difference in preoperative CRP and ALB levels (P＜0.05).The median overall survival of patients with mGPS 0,mGPS 1 and mGPS 2 was 33.6,27.1 and 22.6 months,respectively (P＜0.05);the median progress-free survival of three groups was 32.3,23.4,and 16.5 months,respectively(P＜0.05).The 3-years survival rate of patients with mGPS 2 (24.3％) was significantly lower than that of patients with mGPS 0 (65.59％) and those with mGPS 1 (54.37％,P＜0.05).Conclusion Preoperative mGPS can be used to evaluate the prognosis in patients with hilar cholangiocarcinoma after radical surgery.关键词
肝门部胆管癌/改良型格拉斯哥预后评分/C反应蛋白/低蛋白血症/手术治疗Key words
Cholangiocarcinoma/Modified glasgow prognostic score/C-reactive protein/Low albumin/Surgical treatment引用本文复制引用
李金海,朱明辉,蔡宇,张海峰,薛迪新,蒲青凡..改良型格拉斯哥预后评分对肝门部胆管癌患者手术治疗预后评估的价值研究[J].浙江医学,2018,40(5):468-470,3.
