肿瘤药学2018，Vol.8Issue(2)：244-246,257,4.DOI:10.3969/j.issn.2095-1264.2018.02.27
复方聚乙二醇电解质散联合西沙必利对肺癌化疗便秘患者的疗效分析
The Curative Analysis of cisapride Combined Polyethylene Glycol Electrolyte Powder for Lung Cancer Patients with Constipation after Chemotherapy
摘要
Abstract
Objective To investigate the effect of polyethylene glycol electrolyte powder combined with cisapride for chemotherapy lung cancer patients with constipation and its effect on intestinal function. Methods 80 lung cancer patients adopting chemotherapy with constipa-tion received by our hospital were randomly divided into study group (n=40) and control group (n=40), the control group was simply treated with compound polyethylene glycol electrolyte powder, study group was treated by cisapride on the basis of the control group, the clinical treatment effect, incidence of complications and the gastrointestinal function change of patients were recorded and compared between the two groups. Results As for the treatment effect of patients in study group, the effective rate of combined treatment for patients in study group was signifi-cantly higher than that in the control group (P<0.05); as for the constipation patients improvement, the defecation time of patients in the two groups before treatment had no significant difference (P>0.05). After treatment, the time between taking medicine and the first defecation of the study group was significantly shorter than those of the control group, the total number of patients defecating in the study group was significantly more than that in the control group (P<0.05); the complications, the incidence of complications such as coelenteron stenosis, hepatic disease, and cardiovascular disease in the study group were significantly lower than that in the control group (P<0.05); the gastrointestinal function improvement after surgery, the first exhaust time, and bowel sounds recovery time of patients in the study group were significantly shorter than those of patients in the control group (P<0.05). Conclusion Using polyethylene glycol electrolyte powder combined with cisapride to treat lung cancer patients with constipation after chemotherapy can receive the ideal treatment effect, reduce the incidence of complications, and improve patients' ability of gastrointestinal motility and intestinal cleanliness. Its clinical application should be popularized further.关键词
肺癌化疗便秘/复方聚乙二醇电解质散/西沙必利/肠功能Key words
Chemotherapy/Constipation/Lung cancer/Compound polyethylene glycol electrolyte powder/Cisapride/Intestinal function分类
医药卫生引用本文复制引用
曾军,万中庚,刘健,刘茜,刘彦..复方聚乙二醇电解质散联合西沙必利对肺癌化疗便秘患者的疗效分析[J].肿瘤药学,2018,8(2):244-246,257,4.基金项目
重庆市南岸区第二批科技计划项目(20170140). （20170140）
