肿瘤药学2018,Vol.8Issue(2):283-287,5.DOI:10.3969/j.issn.2095-1264.2018.02.36
不同预防性抗菌药物方案用于肺癌患者围手术期的成本-效果分析
Cost-effectiveness Analysis of Different Preventive Antimicrobials Programs for the Perioperative Patients with Lung Cancer
刘小林 1符一岚 2周国华3
作者信息
- 1. 南京医科大学药理学系,江苏 南京,211166
- 2. 南京医科大学附属肿瘤医院/江苏省肿瘤医院/江苏省肿瘤防治研究所 药学部,江苏 南京,210009
- 3. 湖南省肿瘤医院/中南大学湘雅医学院附属肿瘤医院 药学部临床药学室,湖南 长沙,410013
- 折叠
摘要
Abstract
Objective To conduct the cost-effectiveness analysis of different preventive antimicrobials programs for the perioperative patients with lung cancer. Methods 84 patients in total with lung cancer were selected in our hospital from August 2016 to November 2017. According to the 3 different preventive antimicrobials programs, they were divided into group A, group B and group C, 28 cases in each group. The length of operative time and postoperative hospital stays, the temperature before and after the operation, temperature recovery time, the rate of incision infection, the duration of antibiotics, and the cost of antibiotics were compared between group A, group B and group C. Results The length of operative time, the temperature before and after the operation and the rate of incision infection among the three groups had no significant difference (P>0.05). However, the duration of antibiotics was significantly shortened and the cost of antibacterial drugs decreased significantly in group A compared with the other two groups (P<0.05). Conclusion Using a short course of cefazolin sodium in perioperative period of lung cancer patients is less costly and it can also effectively prevent postoperative infection and reduce antibiotic dosage.关键词
肺癌/预防性抗菌药物/成本-效果分析/围手术期Key words
Lung cancer/Prophylactic antibiotics/Perioperative period/Cost-effectiveness analysis分类
医药卫生引用本文复制引用
刘小林,符一岚,周国华..不同预防性抗菌药物方案用于肺癌患者围手术期的成本-效果分析[J].肿瘤药学,2018,8(2):283-287,5.