肿瘤药学2018，Vol.8Issue(2)：296-300,5.DOI:10.3969/j.issn.2095-1264.2018.02.39
晚期肺癌患者应用培美曲塞+顺铂化疗联合综合性心理干预的效果分析
The Effect of Pemetrexed plus Cisplatin Chemotherapy Combined with Comprehensive Psychological Intervention on Patients with Advanced Lung Cancer
摘要
Abstract
Objective To explore the effect of combined psychological intervention based on pemetrexed and cisplatin chemotherapy in patients with advanced lung cancer and its impact on the quality of life. Methods 160 patients with advanced lung cancer were randomly divided into control group (n=80) and study group (n=80) in our hospital, the patients in the control group were given routine nursing inter-vention and pemetrexed combined with cisplatin. the patients in the study group were given comprehensive psychological intervention on the basis of pemetrexed combined with cisplatin. The treatment efficiency, quality of life score, nursing satisfaction, and anxiety depression score of patients between the two groups were observed and compared. Results the nursing satisfaction of patients in the study group was signifi-cantly higher than that in the control group (P<0.05); the social function, physical function, role function, and cognitive function between the two groups had no significant difference before intervention (P>0.05), life quality score prognosis of patients in study group was significantly higher than that in control group (P<0.05); the effective rate of patients in study group was significantly higher than that in the control group (P<0.05); the anxiety and depression scores of patients between the two group had no significant difference (P<0.05) before the interven-tion; the SAS and SDA of patients in study group were significantly lower than those in the control group patients (P<0.05). Conclusion comprehensive psychological intervention based on pemetrexed combined with cisplatin chemotherapy can significantly improve the quality of life of patients, has high clinical efficacy, and patients' satisfaction. It is worthy of further promotion and application in clinical.关键词
晚期肺癌/培美曲塞/顺铂化疗/效果/生活质量/护理满意度/焦虑抑郁评分Key words
Advanced lung cancer/Pemetrexed/Cisplatin chemotherapy/Effect/Quality of life/Nursing satisfaction/Anxiety and de-pression score分类
医药卫生引用本文复制引用
李小华,叶丽娟,敖冬梅,张灵,吴小玲,周永召..晚期肺癌患者应用培美曲塞+顺铂化疗联合综合性心理干预的效果分析[J].肿瘤药学,2018,8(2):296-300,5.基金项目
四川省卫生厅科研课题(159131). （159131）
