重庆医学2018，Vol.47Issue(15)：1990-1992,1996,4.DOI:10.3969/j.issn.1671-8348.2018.15.004
不同提取物对野棉花抗炎镇痛作用的影响研究
Study on effect of different extraction methods on anti-inflammatory and analgesic activity of Anemone hupehensis
摘要
Abstract
Objective To investigate the effect of different extraction methods on anti-inflammatory and analgesic activity of Anemone hupehensis.Methods The different abstracts were prepared from the whole herb of Anemone hupehensis.The analgesic effect was observed by adopting the mouse torsion and electric heating plate method,and the anti-inflammatory activity was comprehensively evaluated by using the mouse ear tumefaction,toe tumefaction and tampon granulation tumefaction exprements.Results Compared with the blank model group,the anti-inflammatory action difference of low dose in the water layer parts of mouse ear tumefaction,toe tumefaction and tampon granulation tumefaction had no statistical significance(P＞0.05),and the extracting parts of rest doses all had significant anti-inflammatory and analgesic effect (P＜0.05).Ethyl acetate part had strongest activity in the electric heating plate experiment.N-butanol part had strongest activity in the ear tumefaction,toe tumefaction,tampon granulation tumefaction experiments and torsion method.Conclusion The whole herb of Anemone hupehensis has prominent anti-inflammatory and analgesic effect,and the ethyl acetate part E and N-butanol part are main effective parts.关键词
野棉花/抗炎/镇痛/活性部位Key words
Anemone hupehensis Lem/anti-inflammatory/analgesia/active site分类
医药卫生引用本文复制引用
李香,许义红,孙晓惠,韩忠耀,付云燕,伍俊科..不同提取物对野棉花抗炎镇痛作用的影响研究[J].重庆医学,2018,47(15):1990-1992,1996,4.基金项目
黔南医专科研基金资助项目(QNYZ201413). （QNYZ201413）
