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壳聚糖及其衍生物的抗氧化应激和抗炎症作用机制

郑亚光 闫素梅 史彬林 张博綦 赵艳丽

动物营养学报2018,Vol.30Issue(5):1633-1638,6.
动物营养学报2018,Vol.30Issue(5):1633-1638,6.DOI:10.3969/j.issn.1006-267x.2018.05.004

壳聚糖及其衍生物的抗氧化应激和抗炎症作用机制

Anti-Oxidative Stress and Anti-Inflammatory Mechanism of Chitosan and Its Derivatives

郑亚光 1闫素梅 1史彬林 1张博綦 1赵艳丽1

作者信息

  • 1. 内蒙古农业大学动物科学学院,呼和浩特010018
  • 折叠

摘要

Abstract

Chitosan and its derivatives are the products of degradation of chitin by enzymes and acidic hydroly-sis. Due to the biocompatibility and non-toxicity of chitosan,it has the potential value in biological application. This article reviews the anti-oxidation and anti-inflammatory effects of chitosan and its derivatives,the possible mechanism is summarized from nuclear factor-κB(NF-κB)signaling pathway,mitogen-activated protein kina-ses(MAPK)signaling pathway,immunomodulatory factor and lipid metabolism,providing a theoretical basis for its development and utilization.

关键词

壳聚糖及其衍生物/抗氧化/抗炎症/机理

Key words

chitosan and its derivatives/anti-oxidation/anti-inflammatory/mechanism

分类

农业科技

引用本文复制引用

郑亚光,闫素梅,史彬林,张博綦,赵艳丽..壳聚糖及其衍生物的抗氧化应激和抗炎症作用机制[J].动物营养学报,2018,30(5):1633-1638,6.

基金项目

国家自然科学基金(31672463) (31672463)

动物营养学报

OA北大核心CSCDCSTPCD

1006-267X

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