动物营养学报2018,Vol.30Issue(5):1633-1638,6.DOI:10.3969/j.issn.1006-267x.2018.05.004
壳聚糖及其衍生物的抗氧化应激和抗炎症作用机制
Anti-Oxidative Stress and Anti-Inflammatory Mechanism of Chitosan and Its Derivatives
摘要
Abstract
Chitosan and its derivatives are the products of degradation of chitin by enzymes and acidic hydroly-sis. Due to the biocompatibility and non-toxicity of chitosan,it has the potential value in biological application. This article reviews the anti-oxidation and anti-inflammatory effects of chitosan and its derivatives,the possible mechanism is summarized from nuclear factor-κB(NF-κB)signaling pathway,mitogen-activated protein kina-ses(MAPK)signaling pathway,immunomodulatory factor and lipid metabolism,providing a theoretical basis for its development and utilization.关键词
壳聚糖及其衍生物/抗氧化/抗炎症/机理Key words
chitosan and its derivatives/anti-oxidation/anti-inflammatory/mechanism分类
农业科技引用本文复制引用
郑亚光,闫素梅,史彬林,张博綦,赵艳丽..壳聚糖及其衍生物的抗氧化应激和抗炎症作用机制[J].动物营养学报,2018,30(5):1633-1638,6.基金项目
国家自然科学基金(31672463) (31672463)