动物营养学报2018，Vol.30Issue(5)：1662-1667,6.DOI:10.3969/j.issn.1006-267x.2018.05.008
α-酮戊二酸对动物营养物质代谢和一些功能性指标的调控作用及其机理
Mechanism and Regulation of α-Ketoglutaric Acid on Nutrient Metabolism and Some Functional Indicators of Animals
摘要
Abstract
α-ketoglutaric acid is an important substance for the animal organism energy supply in tricarboxylic acid cycle, and an important hub to connecting the carbon metabolism and nitrogen metabolism. α-ketoglutaric acid can improve the immune function of animal organism, affect the metabolism of calcium and phosphorus, increase the bone density and the contents of bone mineral elements, improve the intestinal mucosal structure, and affect some amino acid metabolism positively. In addition,α-ketoglutaric acid can improve the growth per-formance of animals by activating the mammalian target of rapamycin(mTOR)signaling pathway to improve protein synthesis and deposition in skeletal muscle. This article summerized the mechanism and regulation of α-ketoglutaric acid on nutrient metabolism and some functional indicators of animals, and provided evidences for the popularization and application of α-ketoglutaric acid in aquaculture.关键词
α-酮戊二酸/动物/营养物质代谢/调控/机理Key words
α-ketoglutaric acid/animal/nutrient metabolism/regulation/mechanism分类
农业科技引用本文复制引用
郭昊璐,于航宇,孙会..α-酮戊二酸对动物营养物质代谢和一些功能性指标的调控作用及其机理[J].动物营养学报,2018,30(5):1662-1667,6.基金项目
国家重点基础研究发展计划(973计划)(2013CB127306) （973计划）
