分析化学2018，Vol.46Issue(5)：773-779,7.DOI:10.11895/j.issn.0253-3820.171108
基于β-环糊精碳纳米片修饰电极的伏安传感器快速检测磺胺嘧啶
Voltammetric Sensor Based on β-Cyclodextrin-Carbon Nanosheets Modified Electrode for Rapid Determination of Sulfadiazine
摘要
Abstract
Carbon nanosheets load beta-cyclodextrin (β-CD-CNS) as a new modified electrode materials was reported for the electrochemical determination of sulfadiazine(SD). Carbon nanosheets(CNS) were prepared by a new method of ultrasonic electrolysis in which the β-CD was attached on CNS through ultrasonic dispersion method. The β-CD-CNS composite nanomaterials were immobilized onto glassy carbon electrodes with drops of coating method to construct an SD voltammetric sensor. The differential pulse stripping voltammetry (DPSV) was used to characterize the electrocatalytic behavior of the developed sensor. The Effects of some parameters on the response behavior of the sensor such as pH,modification amount,scanning rate,stirring speed,stirring time,deposition potential and time were investigated and optimized. The results indicated that the β-CD-CNS composite nanomaterials had excellent electroactivity for the SD in neutral solution and greatly improved the current response of SD. Under the optimal conditions, the SD had an irreversible characteristic oxidation peak around+0.87 V,and the oxidation peak current ip(μA) had a good linear relationship with the concentration C ( μmol/L) of the SD in concentration range of 0.05 μmol/L-13.5 μmol/L with correlation coefficients of 0.999. The detection limit was 12.2 nmol/L (S/N=3). The sensor was successfully applied for the trace SD determination in water and milk samples and the recoveries from the spiked samples were 80.0%-102% with RSD≤5.2%.关键词
磺胺嘧啶/电化学检测/碳纳米片/β-环糊精/差分脉冲溶出伏安法Key words
Sulfadiazine/Electrochemical detection/Carbon nanosheets/β-Cyclodextrin/Differential pulse stripping voltammetry引用本文复制引用
韦寿莲,利健文,姚夙,欧阳壮,魏承炀..基于β-环糊精碳纳米片修饰电极的伏安传感器快速检测磺胺嘧啶[J].分析化学,2018,46(5):773-779,7.基金项目
本文系广东省医学科研基金项目(No.2016369)、广东食品药品职业学院科研基金项目(No.2015YZ015)和肇庆市科技计划项目(No.2015B010301002)资助 （No.2016369）
