杭州师范大学学报(自然科学版)2018,Vol.17Issue(2):153-158,6.DOI:10.3969/j.issn.1674-232X.2018.02.008
lmo4b对斑马鱼脑发育和内耳形态学的影响研究
Lmo4b's Impacts on the Brain Development and Inner Ear Morphology of Zebrafish
摘要
Abstract
To investigate the effects of lmo4b inhibition on the brain and inner ear development of zebrafish,the lmo4b MO was injected into the Tg(Dat:EGFP)line.The results showed lmo4b inhibition had a significant effect on the brain size of zebrafish.However,there was no significant relation between the number of DA neurons and lmo4b impact on the brain siz.Besides,it was found lmo4b inhibition had a teratogenicity effect on the inner ear development of zebrafish.关键词
斑马鱼/lmo4b/脑/内耳Key words
zebrafish/lmo4b/brain/inner ear分类
生物科学引用本文复制引用
胡旭,黄炜,盛东来..lmo4b对斑马鱼脑发育和内耳形态学的影响研究[J].杭州师范大学学报(自然科学版),2018,17(2):153-158,6.基金项目
国家自然科学基金项目(31300908) (31300908)
浙江省医药卫生科研项目(2015113063) (2015113063)
杭州市医疗卫生及重点专科专病科研攻关专项(20130633B26). (20130633B26)