检验医学与临床2018，Vol.15Issue(10)：1393-1395,3.DOI:10.3969/j.issn.1672-9455.2018.10.006
健康成年男性血栓弹力图参考值范围的研究
The verification of the normal reference interval for thromboelastography in healthy adult males
摘要
Abstract
Objective To verify the reference interval for thromboelastography(TEG)in Chinese healthy a-dult males in Beijing and compare the value with those provided by the manufacturer.Methods A total of 60 peripheral vein blood samples from Chinese healthy adult males in Beijing were enrolled in this study.The T EG parameters including reaction time(R),coagulation time(K),angle(alpha),LY30,coagulation index (CI),ADP induced platelet inhibition rate and maximum amplitude(MA)were determined by using a LEPU-8800 device(LEPU,Beijing).The difference between the actual normal range and manufacturer′s provided reference range was compared.Results The average age of the recruited subjects was(24.84 ± 4.21)years old.T he measured ranges of the T EG parameters w ere R:4.89―10.77 min,K:1.31―4.05 min,alpha-an-gle:42.64―66.16,M A:41.35―62.39 mm,LY30:―2.35% ―1.95%,CI:―7.12―0.32.According to the values of the main indicators including R,K,alpha-angle,and M A,53.3%(32/60)volunteers had at least one indicator outside the manufacturer′s reference range.According to the Kaufmann classification,20%(12/60) volunteers were diagnosed with abnormal coagulation.The ADP inhibition rate was less than 20% in 37 cases, and between 20% ―<50% in 23 cases.The ADP(MA)values ranged between 31―47 mm in 42 cases and >47 mm 18 cases.Conclusion The actual range of TEG parameters for Chinese healthy adult males in Beijing is different from the reference interval provided by the manufacturers.It is necessary to establish the reference intervale of TEG parameters according to the characteristics of local population.关键词
健康男性/血栓弹力图/正常参考值/北京地区Key words
healthy males/thrombelastograghy/reference interval/Beijing region分类
医药卫生引用本文复制引用
秦留安,席少枝,刘佳,刘军,陈韵岱,尹彤..健康成年男性血栓弹力图参考值范围的研究[J].检验医学与临床,2018,15(10):1393-1395,3.基金项目
国家老年疾病临床医学研究中心开放课题资助(NCRCG-PLAGH-2017002) （NCRCG-PLAGH-2017002）
军队后勤科研重点项目资助(BWS17J026). （BWS17J026）
