摘要
Abstract
Objective To evaluate the clinical value of combined detection of lactic acid and NT-proBNP to chronic obstructive pulmonary disease complicated with chronic respiratory failure.Methods From January 2014 to December 2016,a total of 63 cases of chronic respiratory failure in chronic obstructive pulmonary dis-ease in our hospita were collected,chronic obstructive pulmonary disease symptom score of CAT were calcu-lated;and serum lactic acid concentration and NT-proBNP were detected.Comparative analysis of lactic acid and NT-proBNP in different CAT groups were done,the value of lactic acid and NT-proBNP to disease were a-nalysised.Results The results of CAT score between groups of lactic acid and NT-proBNP index were signifi-cantly different and statistically significant(P<0.05).The higher lactic acid,NT-proBNP concentration,the higher the CAT score.In the survival of patients,blood lactate and NT-proBNP were(2.03 ± 0.31)mmol/L, (631.57 ± 42.85)pg/mL,and in the death group,the blood lactic acid and NT-proBNP(4.95 ± 0.46)mmol/L, (1 478.58 ± 120.63)pg/mL,significantly higher than those in survival group,and the difference was statisti-cally significant(P<0.05);lactic acid and NT-proBNP double positive group of patients with severe illness and mortality were significantly higher than the proportion of single detection of lactic acid and NT-proBNP group.Conclusion The detection of lactic acid and NT-proBNP is valuable in judging the severity and progno-sis of COPD patients with chronic respiratory failure,while the combined detection of lactic acid and NT-proB-NP is of greater significance.关键词
慢性阻塞性肺疾病合并呼吸衰竭/乳酸/N-末端脑钠肽前体Key words
chronic obstructive pulmonary disease associated with respiratory failure/lactic acid/NT-proBNP分类
临床医学
