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慢性HBV感染者抗-HBc定量检测的临床意义

侯凤琴 王贵强

临床肝胆病杂志2018,Vol.34Issue(5):915-918,4.
临床肝胆病杂志2018,Vol.34Issue(5):915-918,4.DOI:10.3969/j.issn.1001-5256.2018.05.001

慢性HBV感染者抗-HBc定量检测的临床意义

Clinical value of anti-HBc quantification for chronic HBV infection

侯凤琴 1王贵强2

作者信息

  • 1. 北京大学第一医院感染疾病科暨肝病中心,北京100034
  • 2. 北京大学国际医院感染肝病中心,北京102206
  • 折叠

摘要

Abstract

As the achivement of a major project during the 12th Five-year Plan Period in China,the technique of anti-HBc quantification has been approved for commercial use and holds promise for wide application in clinical practice.Chinese scholars have explored the clinical significance of anti-HBc in various aspects and found that it has great values in the assessment of natural course of chronic hepatitis B virus (HBV) infection and the baseline prediction of antiviral therapy.Studies have shown that anti-HBc is significantly positively correlated with alanine aminotransferase (ALT) and significantly associated with liver inflammation.In chronic HBV infection patients with a normal ALT level,anti-HBc can be used instead as an indicator,with great significance for the development of therapeutic strategy in such patients.

关键词

肝炎,乙型,慢性/肝炎抗体,乙型/丙氨酸转氨酶

Key words

hepatitis B, chronic/hepatitis B antibodies/alanine transaminase

分类

医药卫生

引用本文复制引用

侯凤琴,王贵强..慢性HBV感染者抗-HBc定量检测的临床意义[J].临床肝胆病杂志,2018,34(5):915-918,4.

临床肝胆病杂志

OA北大核心CSTPCD

1001-5256

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