临床肝胆病杂志2018,Vol.34Issue(5):915-918,4.DOI:10.3969/j.issn.1001-5256.2018.05.001
慢性HBV感染者抗-HBc定量检测的临床意义
Clinical value of anti-HBc quantification for chronic HBV infection
侯凤琴 1王贵强2
作者信息
- 1. 北京大学第一医院感染疾病科暨肝病中心,北京100034
- 2. 北京大学国际医院感染肝病中心,北京102206
- 折叠
摘要
Abstract
As the achivement of a major project during the 12th Five-year Plan Period in China,the technique of anti-HBc quantification has been approved for commercial use and holds promise for wide application in clinical practice.Chinese scholars have explored the clinical significance of anti-HBc in various aspects and found that it has great values in the assessment of natural course of chronic hepatitis B virus (HBV) infection and the baseline prediction of antiviral therapy.Studies have shown that anti-HBc is significantly positively correlated with alanine aminotransferase (ALT) and significantly associated with liver inflammation.In chronic HBV infection patients with a normal ALT level,anti-HBc can be used instead as an indicator,with great significance for the development of therapeutic strategy in such patients.关键词
肝炎,乙型,慢性/肝炎抗体,乙型/丙氨酸转氨酶Key words
hepatitis B, chronic/hepatitis B antibodies/alanine transaminase分类
医药卫生引用本文复制引用
侯凤琴,王贵强..慢性HBV感染者抗-HBc定量检测的临床意义[J].临床肝胆病杂志,2018,34(5):915-918,4.