临床肝胆病杂志2018，Vol.34Issue(5)：1111-1114,4.DOI:10.3969/j.issn.1001-5256.2018.05.040
B型利钠肽在肝硬化性心肌病中的作用进展
Advances in the effect of B-type natriuretic peptide and its significance in patients with cirrhotic cardiomyopathy
王亚洁 1陈丽萍 2尚祉胤 1杨敬貌 1艾迎春 1程计林3
作者信息
- 1. 上海市(复旦大学附属)公共卫生临床中心,上海201058
- 2. 佳木斯大学附属第一医院消化内科,黑龙江佳木斯154007
- 3. 温州医科大学附属第一医院消化内科,浙江温州325000
- 折叠
摘要
Abstract
Cirrhotic patients often have an increased cardiac load and impaired myocardial systolic and diastolic functions,which further cause abnormal myocardial structure,and such patients may develop the symptoms of heart failure under stress,which is called cirrhotic cardiomyopathy (CCM).This disease attracts little attention due to its insidious onset.B-type natriuretic peptide (BNP) is secreted by cardiomyocytes and can sensitively reflect the change in ventricular function,and it is widely used in the pathogenesis,treatment,and prognosis of cardiovascular diseases.BNP plays an important role in the diagnosis and treatment of respiratory and renal diseases,and meanwhile,recent studies have shown a significant increase in BNP in cirrhotic patients,which is closely associated with the severity of cirrhotic ascites,varices,and liver dysfunction.BNP can also reveal myocardial injury when there are no obvious symptoms of CCM.This article reviews the expression of BNP and its significance in patients with CCM.关键词
利钠肽,脑/肝硬化/心肌疾病/综述Key words
natriuretic peptide, brain/liver cirrhosis/cardiomyopathies/review分类
医药卫生引用本文复制引用
王亚洁,陈丽萍,尚祉胤,杨敬貌,艾迎春,程计林..B型利钠肽在肝硬化性心肌病中的作用进展[J].临床肝胆病杂志,2018,34(5):1111-1114,4.
