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胆囊癌发病机制及外科治疗的研究进展

张复波 张雅敏

临床肝胆病杂志2018,Vol.34Issue(5):1133-1136,4.
临床肝胆病杂志2018,Vol.34Issue(5):1133-1136,4.DOI:10.3969/j.issn.1001-5256.2018.05.045

胆囊癌发病机制及外科治疗的研究进展

Research advances in the pathogenesis and surgical treatment of gallbladder carcinoma

张复波 1张雅敏1

作者信息

  • 1. 天津市第一中心医院肝胆外科,天津300192
  • 折叠

摘要

Abstract

Gallbladder carcinoma (GBC) is often obscured by some benign diseases in clinical practice and thus unsuspected GBC tends to occur.As for etiology,long-term stimulation by gallstones,gallbladder polyps larger than 1 cm,gallbladder adenoma,and adenomyomatosis of the gallbladder are closely associated with GBC.In the aspect of molecular biology,long non-coding RNA,microRNA,surface growth factor receptor,and some membrane proteins are involved in the development and progression of GBC,which may provide a reference for clinical practice.It is of great importance to perform intraoperative and postoperative surgical management of GBC,which is related to patients'survival.Patients with highly suspected or proven GBC should be converted to open surgery after disease assessment,in order to avoid reoperation.Reoperation should be performed for patients with unsuspected GBC found by postoperative pathological examination,in order to avoid tumor progression and metastasis.

关键词

胆囊肿瘤/基因表达调控,肿瘤/外科手术/综述

Key words

gallbladder neoplasms/gene expression regulation, neoplastic/surgical procedures, operative/review

分类

医药卫生

引用本文复制引用

张复波,张雅敏..胆囊癌发病机制及外科治疗的研究进展[J].临床肝胆病杂志,2018,34(5):1133-1136,4.

临床肝胆病杂志

OA北大核心CSTPCD

1001-5256

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