临床误诊误治2018，Vol.31Issue(5)：4-7,4.DOI:10.3969/j.issn.1002-3429.2018.05.002
获得性免疫缺陷综合征合并脑弓形虫病误诊三例临床分析
Clinical Analysis of Misdiagnosis of Acquired Immune Deficiency Syndrome Complicated with Cerebral Toxo-plasmosis in 3 Cases
摘要
Abstract
Objective To investigate the clinical features,causes of misdiagnosis and preventive measures of acquired immunodeficiency syndrome(AIDS) complicated with cerebral toxoplasmosis. Methods Retrospective anal-ysis was performed on the clinical data of 3 cases of AIDS complicated with cerebral toxoplasmosis which had been mis-diagnosed. Results Three patients presented to our department due to fatigue in the right lower limb for 2 weeks,in-termittent fever,blurred vision and visual decline for more than 1 year,and fever,headache,dizziness,disturbance of consciousness and inactivity of left limb for 3 days,respectively. They were misdiagnosed as having intracranial multi-ple metastatic tumor,toxoplasmosis retinal uveitis,metastatic brain tumor of right temporal lobe, respectively, which were treated accordingly,producing unsatisfactory effects. Subsequently,based on related laboratory tests,CT and MRI examination,they were diagnosed with AIDS complicated with cerebral toxoplasmosis,and given antiviral therapy. One patient died of pulmonary infection due to exacerbation 6 months after treatment. After 2 weeks of treatment,the condi-tion of the other two patients was improved to varying degrees. Conclusion Given similar clinical manifestations of AIDS complicated with cerebral toxoplasmosis to those of many diseases,the condition is easily misdiagnosed. Height-ened perception of the disease, detailed medical history, careful physical examination and differential diagnosis, and timely medical tests can help to reduce or avoid misdiagnosis of AIDS complicated with cerebral toxoplasmosis.关键词
获得性免疫缺陷综合征/弓形虫病；脑/误诊/脑肿瘤Key words
Acquired immunodeficiency syndrome/Toxoplasmosis,brain/Misdiagnosis/Brain neoplasms分类
医药卫生引用本文复制引用
方妍,王涛,周朝鑫..获得性免疫缺陷综合征合并脑弓形虫病误诊三例临床分析[J].临床误诊误治,2018,31(5):4-7,4.基金项目
四川省卫生和计划生育委员会科研课题(15024) （15024）
