临床误诊误治2018，Vol.31Issue(5)：94-98,5.DOI:10.3969/j.issn.1002-3429.2018.05.025
不同通透量血液透析对老年尿毒症患者甲状旁腺激素及钙、磷代谢的影响
lism in Elderly Patients with Uremia
摘要
Abstract
Objective To investigate the effects of different types of flux in hemodialysis on parathyroid hor-mone (PTH),calcium(Ca) and phosphorus(P) metabolism in elderly patients with uremia. Methods A total of 88 elderly patients with uremia admitted to our hospital from 2016 January to 2017 January were divided into low-flux hemodialysis group(LFHD) group and high-flux hemodialysis group(HFHD) group, with 44 cases in each group, according to different types of fluxes in hemodialysis. PTH,Ca,P,serum creatinine (SCr),β2-MG, interleukin-6 (IL-6) and C reactive protein(CRP) level were compared in two groups before treatment and at 6 months after treat-ment. Results After treatment,the levels of P and PTH were significantly lower in HFHD group than those before treatment (P<0.05),and the difference was statistically significant(P<0.05). Six months after treatment, the levels of SCr,β2-MG,IL-6 and CRP in the two groups were decreased compared with those before treatment (P<0.05 or P<0.01),and the levels of those indicators were lower in HFHD group than in LFHD group(P<0.05). Conclusion HFHD can improve the level of PTH and metabolism of Ca and P in elderly patients with uremia,amel-iorate inflammatory response,protect renal function and reduce renal injury.关键词
尿毒症/老年人/肾透析/甲状旁腺激素/钙/磷Key words
Uremia/Aged/Renal dialysis/Parathyroid hormone/Calcium/Phosphorus分类
医药卫生引用本文复制引用
董艳华,王琳琳,朱桂栋..不同通透量血液透析对老年尿毒症患者甲状旁腺激素及钙、磷代谢的影响[J].临床误诊误治,2018,31(5):94-98,5.基金项目
首都卫生发展科研专项资金项目(20171435) （20171435）
