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ADC值对乳腺导管原位癌侵袭成分的研究价值

郭宏兵 刘菲 史新乐 赵一林 邹殿俊

中国医疗设备2018,Vol.33Issue(5):76-79,4.
中国医疗设备2018,Vol.33Issue(5):76-79,4.DOI:10.3969/j.issn.1674-1633.2018.05.020

ADC值对乳腺导管原位癌侵袭成分的研究价值

Effect of ADC Values on Detection of Ductal Carcinoma in Situ

郭宏兵 1刘菲 1史新乐 1赵一林 1邹殿俊1

作者信息

  • 1. 河北北方学院附属第一医院 影像科,河北 张家口 075000
  • 折叠

摘要

Abstract

Objective The purpose of this study is to discuss the diagnostic value of different ADC values on ductal carcinoma in situ (DCIS) so as to evaluate the preoperative prediction invasive component. Methods A total of 69 DCIS female patients with 70 lesions confirmed by pathology during June 2014 and October 2016 were included in this study; all of them underwent preoperative MRI. We selected the highest and lowest ADC value from the region of interest, and calculated the difference value between them. The differences between the DCIS and DCIS invasive component were compared. Results The minimum ADC value in DCIS invasive component was much lower than that of DCIS (P=0.0037). The difference value between maximum ADC and minimum ADC in DCIS invasive component was much higher than that of DCIS (P=0.0007). There was negative correlation between minimum ADC value and difference value (r=0.65). ROC showed that the effective threshold-value of ADC maximum value less than 1.1×10-3mm2/s was contributed to identification of DCIS invasive component and DCIS, with sensibility and specificity of 72% and 77%. Similarly, the effective threshold-value of difference value of ADC higher than 0.23×10-3mm2/s was also contributed to identification of DCIS invasive component and DCIS, with sensibility and specificity of 68% and 76%. Conclusion Both the minimum ADC value and the difference value between the minimum and maximum are helpful for identifying of DCIS invasive component and DCIS, which can help to determine if the sentinel lymph node and axillary lymph node could be swept.

关键词

乳腺导管原位癌/乳腺X线摄影/彩色多普勒超声/磁共振成像/病理组织学

Key words

ductal carcinoma in situ/mammography/color Doppler ultrasound/magnetic resonance imaging/histopathology

分类

医药卫生

引用本文复制引用

郭宏兵,刘菲,史新乐,赵一林,邹殿俊..ADC值对乳腺导管原位癌侵袭成分的研究价值[J].中国医疗设备,2018,33(5):76-79,4.

中国医疗设备

OACSTPCD

1674-1633

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