摘要
Abstract
Objective:To assess sonographic features of thyroid nodules associated with malignancy and to establish a scoring and categorizing method based on sonographic features.Methods:A total of 2 045 patients with 2 045 thyroid nodules were included and divided into 2 groups:benign (1 293) and malignant (752).First,11 sonographic features,including shape,border,margin,internal content,echogenicity,microcalcifications,posterior echo,halo,vascularization distribution,vascularization degree,and SR,were defined,and all nodules were retrospectively evaluated.Second,the features associated with malignancy were selected by statistical analysis and were assigned weightings according to their odds ratios.Third,a total score for each nodule was obtained after the assigned weightings of the suspicious features were summed.Fourth,the malignancy rate of each total score was calculated.Then a modified version of the Thyroid Imaging Reporting and Data System (TI-RADS) was established with reference to the American College of Radiology's Breast Imaging Reporting and Data System.Results:Six independent features associated with malignancy were a taller-than-wide shape,an irregular margin,solid internal content,marked hypoechogenicity and hypoechogenicity,microcalcifications and qualitative hard.The TI-RADS included 5 categories with different malignancy rates:category 3(＜2％),4A(3％～10％),4B(11％～50％),4C(51％～94％),and 5(≥95％).Conclusions:A modified version of TI-RADS was established on the basis of the sonographic features with different weightings according to the relative risk of malignancy.This system could be of great use in predicting the nature of thyroid nodules in a quantified and standardized way and also helping clinicians decide on the clinical management.关键词
甲状腺结节/超声检查,多普勒,彩色Key words
Thyroid nodule/Ultrasonography, Doppler, color分类
医药卫生
