摘要
Abstract
Objective:To explore the value of different sequences of 3T magnetic resonance in the differential diagnosis of benign and malignant breast tumors.To optimize the diagnostic performance of DCE-MRI and DWI by the threshold ADC values.Methods:A retrospective analysis of preoperative MRI images of 573 cases with 608 histopathologically verified breast lesions by surgery or biopsy were conducted.A reading method that adapted ADC thresholds to the assigned BI-RADS classification was developed.Sensitivity,specificity,diagnostic accuracy and the area under the curve (AUC) were calculated.BIRADS-adapted reading was compared with previously published reading methods such as T1WI and T2WI,DWI,T1WI,T2WI and DWI,DCE-MRI in the same population.Result:The sensitivities of T1WI and T2WI,DWI,T1WI,T2WI combined with DWI,DCE-MRI and DCE-MRI combined with DWI were 78.2％,66.2％,92.4％,78.4％ and 94.9％ respectively.And the specificities were 79.7％,97.5％,67.6％,99.1％ and 81.1％,respectively.The AUC was 0.783,0.846,0.909,0.923 and 0.399,respectively.Conclusion:Non-enhanced sequences of 3T magnetic resonance have high sensitivity and low specificity,but it still has some clinical significance when the patient cannot do the DCE-MRI.Multi-parametric breast 3T MRI with BIRADS-adapted reading improves diagnostic accuracy.关键词
乳腺肿瘤/磁共振成像/诊断,鉴别Key words
Breast neoplasms/Magnetic resonance imaging/Diagnosis, differential分类
医药卫生
