临床前期阿尔茨海默病的功能MRI研究进展OACSTPCD
Progress of research on preclinical Alzheimer's disease based on functional MRI
阿尔茨海默病(Alzheimer's disease,AD)是一个连续的病理生理学过程,在临床症状出现前的数十年,人脑就已产生AD特异性的病理学改变.近年来,借助先进的神经影像学技术和生化检测手段,研究人员逐步发现了各种AD相关的生物学标志物,使得在临床前期诊断AD并实施干预成为可能.功能MRI是目前最常用的脑功能成像技术,可揭示疾病早期的脑功能活动特征.本文就近年来基于功能MRI的临床前期AD研究进行综述.
Alzheimer's disease (AD) is considered as a continuously pathophysiological process.Special pathological changes of AD has occurred decades prior to the onset of clinical symptoms.Currently,due to the advanced neuroimaging techniques and biochemical tests,variant AD-related biomarkers are gradually identified,making it possible to diagnose AD in the preclinical stage and further intervene the process of the disease.Functional MRI (fMRI),which is helpfu…查看全部>>
盛灿;刘芳;韩璎
清华大学第一附属医院神经内科,北京100016清华大学第一附属医院神经内科,北京100016首都医科大学宣武医院神经内科,北京100053
医药卫生
阿尔茨海默病磁共振成像
Alzheimer diseaseMagnetic resonance imaging
《中国临床医学影像杂志》 2018 (5)
359-362,4
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