中国免疫学杂志2018，Vol.34Issue(5)：794-800,封3,8.DOI:10.3969/j.issn.1000-484X.2018.05.031
C型凝集素受体CLR对树突状细胞功能的调控效应
Effects of C-type lectin receptors on functional regulation of dendritic cells
邓捷文 1郭振红1
作者信息
- 1. 第二军医大学免疫学教研室暨医学免疫学国家重点实验室,上海200433
- 折叠
摘要
Abstract
Dendritic cells are the most potent professional antigen presenting cells.The expression of C-type lectin receptors (CLR) contributes to the intake of glycoprotein and identification of microbial antigens,which results in antigen information presented to T and B lymphocytes and the ensuing adaptive immune response.The process plays an important role in antifungal or anti-parasitic infection immunity,allergic reactions and tumor immunity.Therefore,it is of great significance to explore the effect of C-type lectin receptors on the regulation of DC function and the development of diseases.The review focuses on the recent research findings on the effect of CLR members on the functional regualtion of DC.关键词
C型凝集素受体/树突状细胞/信号转导/抗真菌感染/过敏反应/免疫应答Key words
C-type lectin receptors/Dendritic cells/Signal transduction/Antifungal immunity/Allergy/Immune response分类
医药卫生引用本文复制引用
邓捷文,郭振红..C型凝集素受体CLR对树突状细胞功能的调控效应[J].中国免疫学杂志,2018,34(5):794-800,封3,8.
