中国畜牧兽医2018，Vol.45Issue(5)：1389-1394,6.DOI:10.16431/j.cnki.1671-7236.2018.05.033
黄牛呼吸道CD3+淋巴细胞分布的研究
Study on Distribution of CD3+Lymphocytes in Cattle Respiratory Tract
摘要
Abstract
CD3+is an important surface marker of T cell population.CD3+lymphocytes w hich are distributed under respiratory tract mucosae as the basis of anti-infective mucosal immunity play an important role in protecting the body against respiratory infection.In order to understand the dis-tribution profile of CD3+lymphocytes and lymphoid tissues in cattle respiratory tract for the mu-cosal immune strategy of respiratory tract,the samples of nasal mucosa,trachea,pulmonary bron-chia and lung from five 7-month-old health cattle were collected and the distribution of CD 3+lym-phocytes and lymphoid tissues was tested by HE staining and immunohistochemistry methods. The results showed that CD3+lymphocytes distributed in mucosal epithelium,below lamina prop-ria and around gland in nose,trachea and pulmonary bronchia and lung.CD3+lymphocytes form diffuse lymphoid tissue in nasal mucosa and lung.The number of the CD3+lymphocytes were the largest in nasal mucosa and lung,followed by trachea and pulmonary bronchia.The results made clear the distribution profile of CD 3+lymphocytes in cattle respiratory tract.It indicated that the respiratory tract of cattle had the basic conditions for initiating local mucosal immunity.This study would provide the basic data for mucosal immunity in respiratory tract and prevention and treatment for respiratory disease in cattle.关键词
黄牛/CD3+淋巴细胞/淋巴组织/呼吸道组织Key words
cattle/CD3+lymphocytes/lymphoid tissue/respiratory tract tissues分类
农业科技引用本文复制引用
李乙江,罗祥波,李佳赟,杨倩,蚌德新,郭兆廷,余绍荣,丁宏,闫信权,张书光,杨科,郭兆卫..黄牛呼吸道CD3+淋巴细胞分布的研究[J].中国畜牧兽医,2018,45(5):1389-1394,6.基金项目
国家自然科学基金项目《一种高效提高新生仔猪肠道免疫力的新机制》(31372465) （31372465）
