中国畜牧杂志2018，Vol.54Issue(5)：25-29,5.DOI:10.19556/j.0258-7033.2018-05-025
拷贝数变异及其在家禽育种中的最新研究进展
Recent Advances in Copy Number Variations in Poultry Breeding
摘要
Abstract
Copy number variations (CNVs) refer to insertions,deletions,or duplications of DNA fragments ranging in length from 50 bp to several megabases (Mb) in comparison with reference genome.CNVs are very important and widespread structure variations which are characterized by wide distribution,high mutation rate,heritability,and heterogeneity.CNVs are widely found in mammals and poultry,which are driving forces for phenotypic diversity,disease resistance,and genetic evolution in livestock and poultry.Poultry is not only an important farm animals,but also an ideal model animal in molecular genetics.In this paper,the history and detecting methods of CNVs are reviewed.In addition,effects of CNVs on phenotypic traits in poultry,the existing problems and applications of CNVs in poultry disease-resistance breeding are deeply analyzed and prospected.关键词
拷贝数变异/遗传标记/经济性状/分子育种/家禽Key words
Copy number variations/Genetic markers/Economic trait/Molecular breeding/Poultry分类
农业科技引用本文复制引用
金四华,杨磊,何婷婷,范心凤,蔺和太,刘平,耿照玉..拷贝数变异及其在家禽育种中的最新研究进展[J].中国畜牧杂志,2018,54(5):25-29,5.基金项目
安徽省重点研究与开发计划项目(1704a07020091) （1704a07020091）
安徽省自然科学基金项目(1808085QC61) （1808085QC61）
安徽农业大学引进与稳定人才项目(yj2017-03) （yj2017-03）
安徽地方畜禽遗传资源保护与生物育种省重点实验室(AKLGRCB2017008) （AKLGRCB2017008）
