摘要
Abstract
Objective To investigate the anatomic index of eyeball including central corneal thickness (CCT),axial length (AL) and corneal curvature (CCV) in primary glaucoma patients and normal controls,and to explore the relationship among CCT,AL and CCV.Methods This was a cross-sectional study.284 subjects (284 eyes) were enrolled,including 75 cases of primary open angle glaucoma (POAG),60 cases of normal tension glaucoma (NTG),89 cases of primary angle closure glaucoma (PACG) and 60 cases of normal controls.Parameters including CCT,CCV and AL were analysis.Results The mean CCT was 528.58±35.11μm,544.96 ±35.92μm,537.44 ±31.74μm,539.80± 31.88μm in NTG,POAG,PACG and normal controls,the mean AL was 24.24±1.41mm,24.30±1.61mm,22.47± 0.99mm,23.73±1.38mm and the mean CCV was 44.82±1.75,44.96±1.78,45.04±1.62,44.75±1.46 respectively.The difference in CCT between POAG and NTG was significant (P=0.005).The other groups showed no significance in CCT (P>0.05).The AL was smaller in PACG than in other groups(P<0.05).POAG and NTG had longer AL than normal controls.CCV showed no significance in all groups.The correlation betweenALandCCVwerer=-0538,P<0.001 (NTG);r =-0.339,P=0.004 (POAG);r=-0.710,P<0.001 (PACG);r=-0.379,P=0.003 (normal).Conclusion In patients with different types of glaucoma,CCT and AL showed some differences while no significant difference in CCV.CCV and AL in all groups showed negative correlation.In addition to the clear relationship between AL and the incidence of PACG,the relationship between the other results and the incidence of glaucoma is not clear.Further research is still needed.关键词
原发性青光眼/中央角膜厚度/眼轴/角膜屈光力Key words
Primary glaucoma/CCT/AL/CCV