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血管内再通术治疗非急性动脉粥样硬化性颈内动脉颅外段闭塞的疗效观察

林喜喜 张君 王伟 张金平 孙丽丽 郑梅梅 赵伟 宋云 韩巨

中国卒中杂志2018,Vol.13Issue(4):304-310,7.
中国卒中杂志2018,Vol.13Issue(4):304-310,7.DOI:10.3969/j.issn.1673-5765.2018.04.003

血管内再通术治疗非急性动脉粥样硬化性颈内动脉颅外段闭塞的疗效观察

Curative Effect Observation of Endovascular Revascularization for Non-acute Atherosclerotic Extracranial Internal Carotid Artery Occlusion

林喜喜 1张君 2王伟 2张金平 2孙丽丽 2郑梅梅 2赵伟 2宋云 2韩巨2

作者信息

  • 1. 261053 潍坊 潍坊医学院临床医学院
  • 2. 山东大学附属千佛山医院神经内科
  • 折叠

摘要

Abstract

Objective To investigate the safety and efficacy of endovascular revascularization in non-acute occlusion of extracranial internal carotid arteries. Methods From March 2015 to May 2017, 17 consecutive patients with non-acute occlusion of extracranial internal carotid arteries received endovascular recanalization therapy and continuous follow-up. All patients received medication for anti-platelet aggregation therapy before and after the operation. The perioperative complications, such as hyperperfusion syndrome, intracranial hemorrhage, stent thrombosis, dissection, etc, and recanalization efficacy were evaluated with the modified Rankin Scale (mRS) and digital subtraction angiography (DSA) follow-up, respectively. Results In all 17 patients, endovascular recanalization was successfully performed in 11 patients, and unsuccessfully performed in 6 patients. The median follow-up time of the 17 patients was 3 (1, 3, 6) months. Six months after the procedure, the median mRS scores were 1 (0-4). Six months after the procedure, the clinical condition of successful recanalization patients was improved in 9, and remained stable in 2; the clinical condition of unsuccessful recanalization patients was improved in 1, and remained stable in 2, which there was still an ischemic attack in 3. Follow-up check with imaging examination was performed in 7 patients, and restenosis occurred in 1 patient. A meaningful improvement in the modified Rankin Scale of successful patients during follow-up was suggested by Wilcoxon signed-rank test results (Z=-2.807, P=0.005). No complications were found in all patients during the perioperative period. Conclusion Endovascular revascularization for the non-acute atherosclerotic extracranial internal carotid artery occlusion is technically feasible, which can improve the short-term prognosis. However, the long-term outcomes need to be further investigated.

关键词

动脉粥样硬化/颈内动脉闭塞/血管内再通/介入治疗

Key words

Atherosclerosis/Carotiarterocclusion/Endovascularevascularization/Interventional treatment

引用本文复制引用

林喜喜,张君,王伟,张金平,孙丽丽,郑梅梅,赵伟,宋云,韩巨..血管内再通术治疗非急性动脉粥样硬化性颈内动脉颅外段闭塞的疗效观察[J].中国卒中杂志,2018,13(4):304-310,7.

基金项目

山东省科技发展计划项目(2010G0020228) (2010G0020228)

中国卒中杂志

OACSTPCD

1673-5765

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