摘要
Abstract
Objective High-resolution magnetic resonance imaging (HR-MRI) was used to diagnose penetrating artery territory infarction ,including penetrating artery disease (PAD) and parent artery plaque occluding penetrating artery (POPA), which belongs to the large-artery atherosclerosis, and clinical features of two groups were compared. Methods Patients with acute striate artery and pontine paramedian artery territory infarction were enrolled as study subjects. According to the criteria of Chinese Ischemic Stroke Subclassification (CISS), cardiogenic stroke, other etiologies and undetermined etiology were excluded. The patients who were eligible for the criteria were examined by high-resolution magnetic resonance imaging (HR-MRI) to evaluate atherosclerosis of the parent artery. Patients with atherosclerotic plaque in the parent arteries were defined as the POPA group, and those without abnormalities were defined as the PAD group. The risk factors and clinical characteristics of the two groups were compared. Results A total of 64 patients with penetrating artery territory infarction were enrolled in this study. POPA was diagnosed in 75.0% of patients, among which, 43.7% patients whose magnetic resonance angiography/transcranial Doppler were normal, while HR-MRI detected the parent arteries with plaques. The general data of two groups were compared. Patients with POPA had a higher frequency of smoking compared with that of the patients with PAD (P=0.028). There were 26 patients in POPA group with striate artery territory infarction and 22 patients with pontine paramedian artery territory infarction. Compared with infarct lesions with PAD, ischemic lesions in POPA patients were relatively larger, shown as multifocal or cluster-like distribution and frequently extended to the surface of the pons base. And neurological deficits was easily to progress. While lesions with PAD were usually small lacunar infarctions or located in the deep of pons. Conclusion In this research, 75.0% of the penetrating artery territory infarction belongs to parent artery atherosclerosis, and HR-MRI has the ability to improve the accuracy of clearing the etiology of ischemic stroke. The risk factors, clinical characteristics and radiological features of POPA patients were different from PAD.关键词
穿支动脉供血区梗死/高分辨率磁共振成像/卒中病因分型Key words
Penetrating arterterritorinfarction/High-resolution magnetic resonancimaging/Stroketiologclassification
