中国卒中杂志2018，Vol.13Issue(4)：384-388,5.DOI:10.3969/j.issn.1673-5765.2018.04.015
ABO血型及基因与缺血性卒中的相关性研究进展
Progress of Correlation between ABO Blood Group & ABO Gene and Cerebral Ischemic Stroke
魏婉 1张灏 1蒋敏海1
作者信息
- 1. 310002 杭州 杭州市第一人民医院神经内科
- 折叠
摘要
Abstract
Recent studies have shown that non-O blood group (A, B or AB) had a higher risk of ischemic stroke than the O blood group in the ABO blood group system, indicating that the ischemic stroke had a correlation with ABO blood group, which may be due to the ABO blood group and effects of genes by plasma von Willebrand factor, low density lipoprotein cholesterin, and inflammatory factors such as soluble select E, soluble select P, Soluble intercellular adhesion molecule 1. Tumor necrosis factor-α and mediated the occurrence of ischemic stroke. Genome-wide association study also have confirmed that ABO blood group gene single nucleotide polymorphism loci was associated with cerebral ischemic stroke. This paper reviews the ABO blood group and the correlation between gene and ischemic stroke of the latest research progress.关键词
ABO血型/基因/缺血性卒中Key words
Abbloogroup/Gene/Ischemic stroke引用本文复制引用
魏婉,张灏,蒋敏海..ABO血型及基因与缺血性卒中的相关性研究进展[J].中国卒中杂志,2018,13(4):384-388,5.
