中成药2018，Vol.40Issue(5)：1050-1053,4.DOI:10.3969/j.issn.1001-1528.2018.05.008
活血逐瘀清毒汤联合常规治疗对脓毒症致急性肾损伤患者的临床疗效
Clinical effects of Huoxue Zhuyu Qingdu Decoction combined with routine treatment on patients with sepsis-induced acute kidney injury
摘要
Abstract
AIM To investigate clinical effects of Huoxue Zhuyu Qingdu Decoction combined with routine treatment on patients with sepsis-induced acute kidney injury.METHODS One hundred and twenty-two patients were randomly and equally divided into control group for a four-week routine treatment,and observation group for a four-week intervention of Huoxue Zhuyu Qingdu Decoction on the basis of routine treatment.RESULTS Significantly decreased post-treatment APACHE Ⅱ,SOFA scores,and TNF-α,IL-6,IL-18,Scr,CysC,NGAL levels in both groups (P ＜ 0.05),and markedly lower values of the indices in the observation group than in the control group were observed (P ＜ 0.05).Meanwhile,the observation group demonstrated its superiority in terms of significantly shorter hospitalization time and lower mortality rate (P ＜ 0.05).CONCLUSION For patients with sepsisinduced acute kidney injury,a combination therapy of Huoxue Zhuyu Qingdu Decoction and routine treatment contributes to a good prognosis due to their synergistic effect in alleviating inflammatory reactions and improving renal injury.关键词
活血逐瘀清毒汤/常规治疗/脓毒症/急性肾损伤Key words
Huoxue Zhuyu Qingdu Decoction/routine treatment/sepsis/acute kidney injury分类
医药卫生引用本文复制引用
厉兆春..活血逐瘀清毒汤联合常规治疗对脓毒症致急性肾损伤患者的临床疗效[J].中成药,2018,40(5):1050-1053,4.基金项目
2017年潍坊市中医药科研立项项目(2017-02-002) （2017-02-002）
